Vol. 6, Issue 2, Part A (2024)

Background: STEMI is a clinical syndrome delineated by electrocardiographic ST elevation and subsequent elevations in myocardial infarction biomarkers, coupled with distinct symptoms indicative of myocardial ischemia. The aim of this work is to evaluate the predictive value of LV 2D-speckle tracking as a TIMI flow predictor in patients with acute STEMI who are undergoing primary PCI.
Methods: This prospective cohort analysis was conducted on a sample of 150 patients diagnosed with STEMI. The patients were stratified into three equal cohorts based on the TIMI flow grades: Group 1: patients with TIMI flow 0, group 2: patients with TIMI flow 1 and 2 and group 3: patients with TIMI flow 3.
Results: There was a highly statistically significant negative correlation between TIMI flow before PCI with both GLS and GCS before and after PCI, while there was positive correlation with GRS. All speckle tracking parameters were good statistically significant predictors of decreased TIMI flow among studied cases, with sensitivity 76% for GLS, 70% for GCS with specificity 65% and 60% respectively and 68.7% and 63.3% respectively test accuracy.
Conclusions: Left ventricular strain imaging demonstrates a robust correlation with TIMI flow rates and may be employed as a non-invasive predictive tool for assessing TIMI flow in patients experiencing acute STEMI who are undergoing primary PCI, as well as for monitoring recovery post- AMI.