Vol. 5, Issue 1, Part A (2023)

Background: Patients with coronary slow flow phenomenon (CSFP) exhibit the following characteristics: Predominantly middle-aged males, the majority have mixed pattern angina, persistent chest pain sensations after therapy, and many have had repeated invasive and non-invasive examinations. 
Objectives: Our study aimed to determine the base of non-invasive predictors of coronary slow flow phenomenon in patients presenting with chronic coronary syndrome.
Patients and Methods: This a case-control study included 100 participants of suspected coronary artery disease were divided into two groups matched in age and sex group I: 50 patients with primary (CSFP) and group II: 50 patients with normal coronary angiography. Each patient was undergoing to demographic data taking, physical investigation, good hydration, restrict fasting hours requested for coronary angiography, 12 lead-ECGs were obtained for each patient at rest, laboratory parameters, coronary angiography, Treadmill exercise ECG, Transthoracic echocardiography to assess the thickness of the LV wall, the interior dimensions of the LV, the LV EF using M-mood method and the aortic propagation velocity. 
Results: Male Sex and CCSA class 3 were significantly decreased in group I compared to group II and male sex,DM, smoker and CCSA class 4 were substantially increase in group I compared to group II (p<0.05). P max, PWd, QTcd at resting ECG, T wave inversion and ST segment depression at stress ECG were significantly increase in group I compared to group II. QTc min was significantly lower in group I compared to group II (p<0.05). LA diameter were significantly increased in group I than group II. Aortic propagation velocity was significantly decreased in group I than group II (p<0.05). Hematocrit, total leucocytic count, mean platelet volume and HsCRP were significantly increase group I compared to group II (p<0.05).
Conclusions: Patients suspected of having a coronary artery disease who are diagnosed with coronary slow flow, male sex, dilated LA, CCSA class 3 or 4, elevated hematocrit value, elevated total leucocytic count, increased mean platelet volume, increased HsCRP, P max, PWd, QTcd, T wave inversion, ST segment depression, and decreased aortic propagation were statistically higher in CSFP patient compared to controls.